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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HGS
All Species:
23.94
Human Site:
T666
Identified Species:
47.88
UniProt:
O14964
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14964
NP_004703.1
777
86192
T666
A
Y
S
S
Y
Q
P
T
P
T
A
G
Y
Q
N
Chimpanzee
Pan troglodytes
XP_511742
777
85768
T666
A
Y
S
S
Y
Q
P
T
P
T
A
G
Y
Q
N
Rhesus Macaque
Macaca mulatta
XP_001111673
777
86015
T666
A
Y
S
S
Y
Q
P
T
P
T
A
G
Y
Q
N
Dog
Lupus familis
XP_540486
782
86005
T670
A
Y
S
S
Y
Q
P
T
P
T
Q
G
Y
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI8
775
85996
T664
A
Y
S
S
Y
Q
P
T
P
T
P
G
Y
Q
S
Rat
Rattus norvegicus
Q9JJ50
776
86228
T665
A
Y
S
S
Y
Q
P
T
P
T
P
G
Y
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083588
751
84100
P643
Y
T
S
Y
Q
P
T
P
A
Q
A
Y
Q
N
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X8
760
85396
P637
P
A
A
I
L
Q
L
P
Q
Q
H
S
I
A
Q
Honey Bee
Apis mellifera
XP_393989
830
92147
T641
P
I
P
Q
L
Q
Q
T
G
G
H
Q
M
G
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783582
784
87687
Q663
Q
Q
Q
Q
Q
P
Q
Q
Q
Q
P
Q
Q
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40343
622
70927
E521
Q
K
P
Q
S
H
V
E
L
A
P
S
D
P
P
Red Bread Mold
Neurospora crassa
Q7RZJ2
724
79729
Y623
A
A
A
P
D
H
S
Y
P
T
L
P
Q
Q
G
Conservation
Percent
Protein Identity:
100
95.5
98.8
92.3
N.A.
93.3
93.4
N.A.
N.A.
N.A.
80
N.A.
N.A.
41.7
47.7
N.A.
49.4
Protein Similarity:
100
96.6
98.9
94.2
N.A.
95.6
95.6
N.A.
N.A.
N.A.
87.5
N.A.
N.A.
55.7
60.9
N.A.
61.3
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
6.6
13.3
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
13.3
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
24.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
17
17
0
0
0
0
0
9
9
34
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
9
0
50
0
9
17
% G
% His:
0
0
0
0
0
17
0
0
0
0
17
0
0
0
0
% H
% Ile:
0
9
0
9
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
17
0
9
0
9
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
42
% N
% Pro:
17
0
17
9
0
17
50
17
59
0
34
9
0
17
17
% P
% Gln:
17
9
9
25
17
67
17
9
17
25
9
17
25
59
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
59
50
9
0
9
0
0
0
0
17
0
0
9
% S
% Thr:
0
9
0
0
0
0
9
59
0
59
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
50
0
9
50
0
0
9
0
0
0
9
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _